Microglia to the rescue
نویسندگان
چکیده
منابع مشابه
Microglia to the rescue
C ells that suffer DNA damage start pumping out a previously undiscovered version of the angiogenesis promoter VEGF, as Mineur et al. report. The variant, which is tough and mobile, might help cancer cells tap new sources of blood. Researchers have already nabbed about 10 versions of VEGF, which many cancer cells overproduce to feed their need for blood. Mineur et al. were studying the effects ...
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Suicide attempt linked to breakdown he Golgi apparatus breaks down temporarily to segregate into daughter cells during mitosis, but during apoptosis the organelle fragments irreversibly. On page 637, Chiu et al. report that cleavage of a critical tethering protein during apoptosis not only drives the fragmentation of the Golgi apparatus, but also appears to help propagate the apoptotic signal. ...
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OVERPRODUCTION OF REACTIVE OXYGEN SPECIES (ROS) in biological systems has been associated with the initiation or aggravation of diverse pathological states (14, 19). The presumed mechanism is through the ability of ROS to induce biochemical alterations in macromolecules such as DNA, lipids, and proteins (4, 14, 17). It has been known for some time that ROS, produced physiologically by leukocyte...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1796iti4